The methylation cycle begins with folate. When methyl tetrahydrofolate reductase (MTHFR) acts on folate, it picks up a methyl group, transforming into methyl tetrahydrofolate (MTHF). MTHF helps to break down the potentially harmful amino acid, homocysteine, and convert it to methionine, an important and beneficial amino acid.
Homocysteine is an amino acid that is a biproduct of the methylation cycle, but it can also be accumulated through various external factors such as excess alcohol or coffee consumption, smoking, or poor diet. Detoxifying the body of excess homocysteine can help protect it from chronic and cardiovascular diseases, stroke, dementia, and osteoporosis.
Betaine is found in most living organisms and helps manage the buildup of homocysteine in the blood. Elevated homocysteine can lead to atherosclerosis and stroke. Betaine helps manage the conversion of homocysteine to methionine, which helps to build strong bones and maintain a healthy liver.
The trio of B vitamins – B2, B6, and folic acid – also help manage homocysteine levels. Vitamin B2 helps maintain the body’s energy supply by converting carbohydrates into adenosine triphosphate (ATP), a compound which helps boost metabolism by transporting energy between cells.
Magnesium carries a myriad of benefits, including healthy bone formation, cardiovascular support, healthy muscle maintenance, and management of head cavity discomfort.