F8 Cardio Support

ONLY FOR REGION: INTERNATIONAL

 154.99

30 day supply

DR PRUSS® F8 formula was created to support cardiovascular health and circulation, and to reduce oxidative stress and cellular energy deficiency using some of the most effective ingredients available, including inositol, taurine, citrulline, and carnitine complemented by vitamins and magnesium.

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Product Benefits

Taurine is an amino acid which occurs naturally in the body. From an athletic standpoint, taurine has been shown to have several health benefits, including those related to endurance and vascular function.

L-citrulline, an amino acid produced in the body, is converted by the kidneys into another amino acid, l-arginine, a precursor to nitric oxide. Nitric oxide is a vasodilator, meaning it expands the arteries to allow greater blood flow during exercise. Vasodilation also helps to lower blood pressure, so citruline has been used in the treatment of hypertension.

Carnitine is an amino acid which plays a key role in energy production, and has been shown to facilitate the transport of long chain fatty acids into the mitochondrial matrix, triggering cardioprotective benefits through reduced oxidative stress and inflammation. Studies on carnitine have highlighted its effectiveness in the treatment of chronic heart failure, arrhythmia, peripheral vascular disease, and acute ischemia.

N-acetyl-l-cysteine, or NAC, performs a number of benefits. Together with glycine and glutamine, NAC produces glutathione, a powerful antioxidant; it also helps maintain healthy liver function and healthy lung function.

N-acetylcysteine ​​and carnitine can cross the blood-brain barrier due to their antioxidant properties, and thus help maintain the health of blood vessels and nerve cells. These antioxidants also have beneficial effects on mitochondrial and circulatory functions, methylation, and homocysteine ​​metabolism.

Inositol is a carbohydrate found naturally in the body. Inositol helps to keep anxiety in the normal range and plays a role in the processing of serotonin, an important neurotransmitter in the brain often associated with feelings of well-being and happiness.

Magnesium has many benefits, from healthy bone formation to cardiovascular health to healthy muscle maintenance. Pantothenic acid is included for additional benefits.

Validation

EFSA Health Claims:

  • Pantothenic acid contributes to:
    • normal energy-yielding metabolism
    • normal mental performance
    • normal synthesis and metabolism of steroid hormones, vitamin D and some neurotransmitters
    • reduction of tiredness and fatigue

References

Magnesium

  • Di Nicolantonio JJ, O’Keefe JH, Wilson W. Subclinical magnesium deficiency: a principal driver of cardiovascular disease and a public health crisis [published correction appears in Open Heart. 2018 Apr 5;5(1):e000668corr1]. Open Heart. 2018;5(1):e000668. Published 2018 Jan 13. doi:10.1136/openhrt-2017-000668

Inositol

  • Minozzi M, Nordio M, Pajalich R. The Combined therapy myo-inositol plus D-Chiro-inositol, in a physiological ratio, reduces the cardiovascular risk by improving the lipid profile in PCOS patients. Eur Rev Med Pharmacol Sci. 2013;17(4):537-540.
  • Chhetri DR. Myo-Inositol and Its Derivatives: Their Emerging Role in the Treatment of Human Diseases. Front Pharmacol. 2019;10:1172. Published 2019 Oct 11. doi:10.3389/fphar.2019.01172

Citrulline

  • Allerton TD, Proctor DN, Stephens JM, Dugas TR, Spielmann G, Irving BA. l-Citrulline Supplementation: Impact on Cardiometabolic Health. Nutrients. 2018;10(7):921. Published 2018 Jul 19. doi:10.3390/nu10070921
  • Romero MJ, Platt DH, Caldwell RB, Caldwell RW. Therapeutic use of citrulline in cardiovascular disease. Cardiovasc Drug Rev. 2006;24(3-4):275-290. doi:10.1111/j.1527-3466.2006.00275.x
  • Morita M, Sakurada M, Watanabe F, et al. Effects of Oral L-Citrulline Supplementation on Lipoprotein Oxidation and Endothelial Dysfunction in Humans with Vasospastic Angina. Immunol Endocr Metab Agents Med Chem. 2013;13(3):214-220. doi:10.2174/18715222113139990008
  • Barkhidarian B, Khorshidi M, Shab-Bidar S, Hashemi B. Effects of L-citrulline supplementation on blood pressure: A systematic review and meta-analysis. Avicenna J Phytomed. 2019;9(1):10-20.

Carnitine

  • Song X, Qu H, Yang Z, Rong J, Cai W, Zhou H. Efficacy and Safety of L-Carnitine Treatment for Chronic Heart Failure: A Meta-Analysis of Randomized Controlled Trials. Biomed Res Int. 2017;2017:6274854. doi:10.1155/2017/6274854
  • Kaneko M, Fukasawa H, Ishibuchi K, Niwa H, Yasuda H, Furuya R. L-carnitine Improved the Cardiac Function via the Effect on Myocardial Fatty Acid Metabolism in a Hemodialysis Patient. Intern Med. 2018;57(24):3593-3596. doi:10.2169/internalmedicine.1055-18
  • Wang ZY, Liu YY, Liu GH, Lu HB, Mao CY. l-Carnitine and heart disease. Life Sci. 2018;194:88-97. doi:10.1016/j.lfs.2017.12.015
  • Retter AS. Carnitine and its role in cardiovascular disease. Heart Dis. 1999;1(2):108-113.

Taurine

  • Xu YJ, Arneja AS, Tappia PS, Dhalla NS. The potential health benefits of taurine in cardiovascular disease. Exp Clin Cardiol. 2008;13(2):57-65.
  • Schaffer S, Kim HW. Effects and Mechanisms of Taurine as a Therapeutic Agent. Biomol Ther (Seoul). 2018;26(3):225-241. doi:10.4062/biomolther.2017.251
  • Wójcik OP, Koenig KL, Zeleniuch-Jacquotte A, Costa M, Chen Y. The potential protective effects of taurine on coronary heart disease. Atherosclerosis. 2010;208(1):19-25. doi:10.1016/j.atherosclerosis.2009.06.002

Supplement facts

SUPPLEMENT FACTS
Serving Size: 2 Vials
Servings per Container: 15

AMOUNT PER SERVING % Daily Value
Taurine (Free-Form) 2000 mg **
Inositol (from Myo-inositol) 2000 mg **
Citrulline (from citrulline malate) 1700 mg mg
Carnitine (from Acetyl-l-Carnitine) 1400 mg **
NAC (N-acetylcysteine) 600 mg **
Pantothenic acid (as calcium salt) 500 mg 10000%
Magnesium (from magnesium bisglycinate) 150 mg 36%

** Daily Value not established.

Directions: As a dietary supplement for adults, consume two (2) vials daily, with or after meals., or as recommended by a healthcare practitioner. Mix with 8 oz./250 ml (one glass) of water.